Product usage

Hyaluronidase has been used in medical applications for over 60 years. The US Food and Drug Administration approved indications are (1) for subcutaneous fluid infusion, (2) to increase absorption and dispersion of drugs in subcutaneous tissue and to manage extravasation, and (3) to promote the absorption of radiopaque agents in urinary tract angiography. Hyaluronidase has also been approved and used for the purpose of increasing hematoma absorption in Europe. In addition, with the increasing popularity of hyaluronic acid filler, hyaluronidase has become an essential drug to dissolute misplaced fillers and to treat complications after injections.